Blar i Bergen Open Research Archive på forfatter "Hu, Jiang"
-
Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia
St-Louis, Johanna L.; el Jellas, Khadija; Velasco, Kelly; Slipp, Brittany A.; Hu, Jiang; Helgeland, Geir; Steine, Solrun; De Jesus, Dario F.; Kulkarni, Rohit N.; Molven, Anders (Journal article; Peer reviewed, 2023)Congenital hyperinsulinism of infancy (CHI) can be caused by a deficiency of the ubiquitously expressed enzyme short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD). To test the hypothesis that SCHAD-CHI arises from a specific ... -
Leptin receptor signaling regulates protein synthesis pathways and neuronal differentiation in pluripotent stem cells
Gupta, Manoj K.; Vethe, Heidrun; Softic, Samir; Rao, Tata Nageswara; Wagh, Vilas; Shirakawa, Jun; Barsnes, Harald; Vaudel, Marc; Takatani, Tomozumi; Kahraman, Sevim; Sakaguchi, Masaji; Martinez, Rachael; Hu, Jiang; Bjørlykke, Yngvild; Ræder, Helge; Kulkarni, Rohit N. (Journal article; Peer reviewed, 2020)The role of leptin receptor (OB-R) signaling in linking pluripotency with growth and development and the consequences of dysfunctional leptin signaling on progression of metabolic disease is poorly understood. Using a ...